U-Blot® Ephrin-A1 Rabbit mAb
Ucallm_WR5745-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | Ephrin-A1 |
| Reactivity | Human |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | 24kD |
| MW(Observed) | 25kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1707R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | EFNA1 EPLG1 LERK1 TNFAIP4 |
| Protein Name | Ephrin-A1 |
| Other Name | EFNA1; / EPLG1; / LERK1; / TNFAIP4; / Ephrin-A1; / Ephrin-A1; / EPH-related receptor tyrosine kinase ligand 1; / LERK-1; / Immediate early response protein B61; / Tumor necrosis factor alpha-induced protein 4; / TNF alpha-induced protein 4; / [Cleaved into: Ephrin-A1, secreted form] |
| Species | Human |
| Gene ID | 1942 |
| Uniprot | P20827, |
| Species.1 | Mouse |
| Gene ID.1 | 13636 |
| Uniprot.1 | P52793, |
| Species.2 | Rat |
| Gene ID.2 | 94268 |
| Uniprot.2 | P97553 |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor .; [Ephrin-A1, secreted form]: Secreted . |
| Tissue Expression | Brain. Down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells (at protein level). |
| Signaling_pathway | Human Diseases >> Cancer: overview >> MicroRNAs in cancer;Environmental Information Processing >> Signal transduction >> MAPK signaling pathway;Environmental Information Processing >> Signal transduction >> Ras signaling pathway;Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway;Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway |
| Research Areas | >>MAPK signaling pathway; / >>Ras signaling pathway; / >>Rap1 signaling pathway; / >>PI3K-Akt signaling pathway; / >>Axon guidance; / >>MicroRNAs in cancer |
| Function | induction:By TNF-alpha and interleukin-1 beta.,similarity:Belongs to the ephrin family.,subunit:Binds to the receptor tyrosine kinases EPHA2, EPHA4, EPHA5, EPHA6 and EPHA7. Also binds with low affinity to EPHA1., |
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