Specifications
| Size | 50μL/100μL |
| Target | FCGRT |
| Reactivity | Human |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 40kD |
| MW(Observed) | 43kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1800R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | FCGRT FCRN |
| Protein Name | FCGRN |
| Other Name | |
| Species | Human |
| Gene ID | 2217 |
| Uniprot | P55899, |
| Species.1 | Mouse |
| Gene ID.1 | 14132 |
| Uniprot.1 | Q61559, |
| Species.2 | Rat |
| Gene ID.2 | 29558 |
| Uniprot.2 | P13599 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein . Endosome membrane . |
| Tissue Expression | Expressed in full-term placenta, heart, lung, liver, muscle, kidney, pancreas, and both fetal and adult small intestine. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus.,similarity:Belongs to the immunoglobulin superfamily.,subunit:FcRn complex consist of two subunits: p51, and p14 which is equivalent to beta-2-microglobulin. It forms an MHC class I-like heterodimer., |
