Name: U-Blot® Ki-67 Mouse mAb
SKU: WM1794
Price: 268 USD
Availability: InStock

U-Blot® Ki-67 Mouse mAb

Ucallm_WM1794-50

Price range: $268.00 through $328.00

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50μl

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SKU: WM1794-100

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Product details

Background:This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Specifications

Target	Ki 67
Reactivity	Human
Applications	IF, WB
MW(Calculated)	359kD
MW(Observed)	359kD
Host Species	Mouse
Isotype	Mouse IgG1/Kappa
Conjugate/Modification	Unmodified
Modification
Recommended Dilution Ratio	WB 2000-10000; IF 1:200-1:1000;
Formulation	PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
Purification	Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Purity
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	PTR1448
Immunogen	The specific immunogen used to produce this antibody is proprietary information.
Sequence
Specificity	Endogenous
Gene Name	MKI67
Protein Name	Ki 67
Other Name	MKI67; / Antigen KI-67
Species	Human
Gene ID-1	4288
Uniprot	P46013
Species.1
Gene ID-2
Uniprot.1
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Background	This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009],
Cellular Localization	Nucleus
Tissue Expression	Nuclear
Signaling_pathway
Research Areas
Function	developmental stage:Expression of this antigen occurs preferentially during late G1, S, G2 and M phases of the cell cycle, while in cells in G0 phase the antigen cannot be detected.,Function:Thought to be required for maintaining cell proliferation.,online information:Ki-67 entry,similarity:Contains 1 FHA domain.,subcellular location:Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix. In mitosis, it is present on all chromosomes.,subunit:Interacts with KIF15. Binds through the FHA domain to MKI67IP.,
RRID

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U-Blot® Ki-67 Mouse mAb

Product details

Specifications

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U-Blot® Ki-67 Mouse mAb

Product details

Specifications

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