U-Blot® Histone H4 (Acetyl Lys8) Rabbit pAb
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Price range: $700.00 through $1,750.00
Product details
Background:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015],
Specifications
| Target | Histone H4 |
| Reactivity | Human, Mouse, Wide Range Predicted |
| Application | ChIP,ChIP-Seq,WB,IF,DB,ICC |
| MW(Calculated) | |
| MW(Observed) | 8 kDa |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Modification | Acetyl |
| Modification site | Lys8 |
| Recommended dilution ratio | WB 0.1 - 1 µg/ml dilution; ChIP 5 - 10 µg per ChIP; ChIP-Seq 5 - 10 µg each; ICC/IF 1 µg/ml dilution |
| Formulation | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
| Source | |
| Purification | Protein A Chromatography |
| Purity | |
| Storage | -20°C/2 year. Avoid freeze/thaw cycles. |
| Concentration | 1 µg/µl |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | This Histone H4 acetyl Lys8 antibody was raised against a peptide containing acetyl Lys8 of human Histone H4. |
| Sequence | |
| Specificity | |
| Gene name | HIST1H4A/HIST1H4B/HIST1H4C/HIST1H4D/HIST1H4E/HIST1H4F/HIST1H4H/HIST1H4I/HIST1H4J/HIST1H4K/HIST1H4L/HIST2H4A/HIST2H4B/HIST4H4 |
| Protein name | Histone H4 |
| Alternative name | HIST1H4A;H4/A;H4FA;HIST1H4B;H4/I;H4FI;HIST1H4C;H4/G;H4FG;HIST1H4D;H4/B;H4FB;HIST1H4E;H4/J;H4FJ;HIST1H4F;H4/C;H4FC;HIST1H4H;H4/H;H4FH;HIST1H4I;H4/M;H4FM;HIST1H4J;H4/E;H4FE;HIST1H4K;H4/D;H4FD;HIST1H4L;H4/K;H4FK;H4K8AC |
| Organism-1 | Human |
| Gene ID‑1 | 121504;554313;8294;8359;8360;8361;8362;8363;8364;8365;8366;8367;8368;8370 |
| SwissProt-1 | P62805 |
| Organism-2 | Mouse |
| Gene ID‑2 | 100041230 |
| SwissProt-2 | P62806 |
| Organism-3 | Rat |
| Gene ID‑3 | 100360950 |
| SwissProt-3 | P62804 |
| Organism-4 | |
| Gene ID‑4 | |
| SwissProt-4 | |
| Cellular Localization | |
| Unnamed: 38 | |
| Unnamed: 39 |
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