Product details
Background：Tryptase alpha/beta-1 (β-tryptase/TPSAB1) is a ~30 kDa protein. Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates.
1. Jackson, NE. et al. (2008) The Journal of biological chemistry 283, 34178-87.
PMID: 18854315
