Specifications
| Size | 50μL/100μL |
| Target | KOR-1 |
| Reactivity | Mouse, Rat |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 43kD |
| MW(Observed) | 60kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1701R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | OPRK1 |
| Protein Name | Kappa-type opioid receptor |
| Other Name | OPRK1; / OPRK; / Kappa-type opioid receptor; / K-OR-1; / KOR-1 |
| Species | Human |
| Gene ID | 4986 |
| Uniprot | P41145, |
| Species.1 | Mouse |
| Gene ID.1 | 18387 |
| Uniprot.1 | P33534, |
| Species.2 | Rat |
| Gene ID.2 | 29335 |
| Uniprot.2 | P34975 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . |
| Tissue Expression | Detected in brain and placenta. |
| Signaling_pathway | |
| Research Areas | >>Neuroactive ligand-receptor interaction |
| Function | Function:Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for dynorphins. May play a role in arousal and regulation of autonomic and neuroendocrine functions.,online information:Kappa opioid receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts with SLC9A3R1. Interacts with GABARAPL1., |
