U-Blot® OX40L hIgG1 Reference Antibody (Oxebio)
UcallM
$999.00
Product details
Background：OX40L, is not expressed on resting antigen presenting cells, but is following their activation. Expression of OX40 is dependent on full activation of the T cell; without CD28, expression of OX40 is delayed and of fourfold lower levels. OX40L binds to OX40 receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response beyond the first few days and onwards to a memory response due to its ability to enhance survival. OX40 also plays a crucial role in both Th1 and Th2 mediated reactions in vivo.
Specifications
| Target | OX40L |
| Reactivity | |
| Applications | Flow cytometry |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Human |
| Isotype | IgG1 |
| Conjugate/Modification | Unconjugated |
| Modification | |
| Recommended Dilution Ratio | |
| Formulation Buffer | Phosphate-buffered solution, pH 7.2-7.4. |
| Source | |
| Purification | |
| Purity | > 95% as determined by SDS-PAGE |
| Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -197℃ long term.Avoid repeated freeze-thaw. |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | Oxelumab |
| Immunogen | |
| Sequence | |
| Specificity | |
| Gene Name | |
| Protein Name | |
| Other Name | CD134L, CD252, GP34, OX-40L, OX4OL, TNLG2B, TXGP1 |
| Species | |
| Gene ID | |
| Uniprot | |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Organism-4 | |
| GeneID-4 | |
| SwissProt-4 | |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | |
| RRID |
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