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Background:Carboxyethyl-Cysteine (CEC) is a novel post-translational modification occurring on cysteine residues of proteins. This modification is formed by covalently attaching a carboxyethyl group to the thiol group (-SH) of cysteine, generating a stable thioether linkage. CEC modification is widely distributed on histones and various functional proteins, and has been reported to be involved in cellular oxidative stress, metabolic regulation, protein stability, and a variety of physiological and pathological processes, making it an important target in protein modification and disease research.
