U-Blot® Pan-D-Lactyllysine Rabbit pAb
Product details
Background:D-Lactyllysine (K₍D_x001E_la₎) is the D_x001E_stereoisomer of lysine lactylation, a novel type of lysine acylation post_x001E_translational modification. By conjugating a D_x001E_lactyl group to lysine residues, K₍D_x001E_la₎ is mainly generated via non_x001E_enzymatic pathways from glycolysis byproducts and exists on both histone and non_x001E_histone proteins. It participates in chromatin remodeling, gene transcription, and cellular metabolic stress responses, and is closely associated with tumorigenesis, inflammation, metabolic reprogramming, and other pathological processes, serving as a key target in metabolic_x001E_epigenetic crosstalk research.
Specifications
| Target | D-Lactyllysine |
| Reactivity | Species Independent |
| Application | WB, IHC-P, ICC/IF, FC |
| MW(Calculated) | Multiple |
| MW(Observed) | Multiple |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Modification | Lysine lactylation |
| Modification Site | Lys(K) |
| Recommended dilution ratio | WB 1:1000;IHC-P 1:100-1:200;ICC/IF 1:100-1:200;FC 1:100-1:200 |
| Composition | PBS, Glycerol, BSA,NaN3 |
| Purification process | Protein A |
| Storage | Store at -20°C. Avoid repeated freeze-thaw cycles |
| Stability | Stable for 12 months from date of receipt / reconstitution. |
| Concentration | |
| Clonal | Polyclonal |
| Clone Number | |
| Immunogen | polypeptide |
| Gene Name | |
| Protein Name | |
| Alternative name | KD-la |
| Organism-1 | |
| Gene ID | |
| SwissProt-1 | |
| Cellular Localization |
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