U-Blot® PD1 hIgG1 Reference Antibody (Perbio)

$999.00

SKU: WE2696-50
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Product details

Background:Programmed cell death protein-1 (PD-1) is an inhibitory immune checkpoint primarily expressed by immune cells. In the tumor microenvironment, PD-1 binds to its ligands PD-L1 and PD-L2, inhibiting T cell activation and proliferation, which allows tumor cells to evade immune system surveillance. Peresolimab, a monoclonal antibody against PD-1(programmed death protein 1) , falls into the category of immune checkpoint inhibitors. It is mainly used in cancer therapy, by blocking the interaction between PD-1 and its ligands PD-L1 and PD-L2, enhance the body’s immune system against tumor cells.

Specifications

TargetPD1
Reactivity
ApplicationsFlowCytometry
MW(Calculated)
MW(Observed)
Host SpeciesHuman
IsotypeIgG1
Conjugate/ModificationUnconjugated
Modification
Recommended Dilution Ratio
Formulation BufferPhosphate-buffered solution, pH 7.2-7.4.
Source
Purification
Purity> 95% as determined by SDS-PAGE
StorageStore at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term.Avoid repeated freeze-thaw.
Concentration
ClonalityMonoclonal
Clone NumberPeresolimab
Immunogen
Sequence
Specificity
Gene Name
Protein Name
Other NameCD279,PD-1, PDCD1, SLEB2, hPD-1, hPD-l, hSLE1
Species
Gene ID
Uniprot
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Organism-4
GeneID-4
SwissProt-4
Cellular Localization
Tissue Expression
Signaling_pathway
Research Areas
Function
RRID
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