U-Blot® Phospho S6 Ribosomal Protein (Ser235/236) Mouse mAb

Price range: $288.00 through $368.00

SKU: WT9053-100
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Product details

Background:
Ribosomal protein S6 (rpS6 or eS6) is a component of the 40S ribosomal subunit and is therefore involved in translation. Mouse model studies have shown that phosphorylation of eS6 is involved in the regulation of cell size, cell proliferation, and glucose homeostasis. Important S6 ribosomal protein phosphorylation sites include several residues (Ser235, Ser236, Ser240, and Ser244) located within a small, carboxy-terminal region of the S6 protein.

Specifications

ClonalRecombinant monoclonal
Clone NumberW-R28
Alternative name
TargetPhospho-S6 Ribosomal Protein (Ser235/Ser236)
ReactivityHuman
MW(Calculated)32kDa
MW(Observed)32kDa
ApplicationWB、ICC/IF
Host SpeciesMouse
IsotypeIg2B/Kappa
ConjugateUnconjugated
ModificationPhosphorylation
Modified site
Recommended dilution ratioWB 1:500-1000、ICC/IF 1:50
CompositionPBS, Glycerol, BSA
Purification processProtein G
StorageStore at -20°C. Avoid repeated freeze-thaw cycles
StabilityStable for 12 months from date of receipt / reconstitution.
Unnamed: 18
Unnamed: 19
ImmunogenPolypeptide
Sequence
SpecificitySpecific for S6 Ribosomal Protein only when phosphorylated at Ser235/Ser236
Gene nameRPS6
Protein Name40S ribosomal protein S6
Unnamed: 25
Organism-1Human
GeneID-16194
SwissProt-1P62753
Organism-2
GeneID-2
SwissProt-2
Organism-3
GeneID-3
SwissProt-3
Organism-4
GeneID-4
SwissProt-4
Cellular LocalizationCytosol, Endoplasmic reticulum, Nucleus
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