U-Blot® Research Grade Cirevetmab
Ucallm.jpg
$9,999.00
Product details
Background：Cirevetmab (ZTS-00521426) is an immunoglobulin G2-kappa, Canis lupus familiaris TGFB1 caninized monoclonal antibody. Cirevetmab is an immunomodulator.
• TGFB1 induces fetal reprogramming and enhances intestinal regeneration., PMID:37865088
• Biomarkers for the identification of cardiac fibroblast and myofibroblast cells., PMID:29987445
• Association between TGF-β gene polymorphism and myopia: A systematic review and meta-analysis., PMID:35905284
• A fibroblast-dependent TGF-β1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis., PMID:38980870
• The effect of TGF-β1 polymorphisms on pulmonary disease progression in patients with cystic fibrosis., PMID:35525938
• Lack of association between the TGF-β(1) gene and development of COPD in Asians: a case-control study and meta-analysis., PMID:21556788
• TGF-β and Diabetic Nephropathy: Lessons Learned Over the Past 20 Years., PMID:32039767
• Direct effect of transforming growth factor-beta 1 (TGF-β1) on human apical papilla cell proliferation and mineralisation., PMID:34596309
• Concentration change of TGF -β 1 in aqueous humor of rabbits., PMID:24507648
• TGF-beta 1 codon 10 polymorphism is associated with cerebral SVD., PMID:22030425
Specifications
| Target | TGFB1/TGF-beta-1 |
| Reactivity | Dog |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Caninized |
| Isotype | IgG2, kappa |
| Conjugate/Modification | |
| Modification | |
| Recommended Dilution Ratio | |
| Composition | 0.01M PBS, pH 7.4. |
| Purification Process | Protein A/G purified from cell culture supernatant. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Storage Condition | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | |
| Immunogen | Mammalian Cells |
| Gene Name | |
| Protein Name | |
| Alias | TGFB1/TGF-beta-1 |
| Species | |
| Gene ID-1 | P54831 |
| Uniprot | |
| Species.1 | |
| Gene ID | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.1 | |
| Uniprot.2 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Description | Background：Cirevetmab (ZTS-00521426) is an immunoglobulin G2-kappa, Canis lupus familiaris TGFB1 caninized monoclonal antibody. Cirevetmab is an immunomodulator.<br>• TGFB1 induces fetal reprogramming and enhances intestinal regeneration., PMID:37865088<br />• Biomarkers for the identification of cardiac fibroblast and myofibroblast cells., PMID:29987445<br />• Association between TGF-β gene polymorphism and myopia: A systematic review and meta-analysis., PMID:35905284<br />• A fibroblast-dependent TGF-β1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis., PMID:38980870<br />• The effect of TGF-β<sub>1</sub> polymorphisms on pulmonary disease progression in patients with cystic fibrosis., PMID:35525938<br />• Lack of association between the TGF-β(1) gene and development of COPD in Asians: a case-control study and meta-analysis., PMID:21556788<br />• TGF-β and Diabetic Nephropathy: Lessons Learned Over the Past 20 Years., PMID:32039767<br />• Direct effect of transforming growth factor-beta 1 (TGF-β1) on human apical papilla cell proliferation and mineralisation., PMID:34596309<br />• Concentration change of TGF -β 1 in aqueous humor of rabbits., PMID:24507648<br />• TGF-beta 1 codon 10 polymorphism is associated with cerebral SVD., PMID:22030425<br /> |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function |
Please login to post questions
Related products
