Product details
Background：Veligrotug is an IgG1-kappa, anti-IGF1R (insulin-like growth factor 1 receptor, CD221) chimeric monoclonal antibody.
• Insulin-like growth factor 2 drives fibroblast-mediated tumor immunoevasion and confers resistance to immunotherapy., PMID:39545420
• Insulin-like growth factor-1 receptor crosstalk with integrins, cadherins, and the tumor microenvironment: sticking points in understanding IGF1R function in cancer., PMID:37490874
• Insulin-Like Growth Factor-1 (IGF-1) and Its Monitoring in Medical Diagnostic and in Sports., PMID:33557137
• CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities., PMID:32238925
• IGF1R is an entry receptor for respiratory syncytial virus., PMID:32494007
• Endothelial insulin-like growth factor-1 signalling regulates vascular barrier function and atherogenesis., PMID:40171617
• Insulin-like growth factor-1 signaling in cardiac aging., PMID:28847512
• IGF1R-phosphorylated PYCR1 facilitates ELK4 transcriptional activity and sustains tumor growth under hypoxia., PMID:37777542
• Expression of Insulin-Like Growth Factor Type 1 Receptor Is Linked to Inflammation in Adamantinomatous Craniopharyngioma., PMID:34915523
• Insulin-Like Growth Factor 1 Receptor Drives Hepatocellular Carcinoma Growth and Invasion by Activating Stat3-Midkine-Stat3 Loop., PMID:33559791
