Product details
Background：Magrolimab is a first-in-class investigational monoclonal antibody against CD47 and macrophage checkpoint inhibitor that is designed to interfere with recognition of CD47 by the SIRPα receptor on macrophages, thus blocking the
• Isolation and characterization of CD47 glycoprotein: a multispanning membrane protein which is the same as integrin-associated protein (IAP) and the ovarian tumour marker OA3., PMID:7998989
• Integrin-associated protein (CD47) and its ligands., PMID:11306274
• Integrin-associated protein (CD47/IAP) contributes to T cell arrest on inflammatory vascular endothelium under flow., PMID:11156950
• Rh-related antigen CD47 is the signal-transducer integrin-associated protein., PMID:8294396
• Membrane mobility and clustering of Integrin Associated Protein (IAP, CD47)–major differences between mouse and man and implications for signaling., PMID:16697668
• Integrin-associated protein/CD47 regulates motile activity in human B-cell lines through CDC42., PMID:10891456
• Integrin-associated protein (CD47) is a comitogenic molecule on CD3-activated human T cells., PMID:8992983
• Molecular cloning and functional characterization of the pig homologue of integrin-associated protein (IAP/CD47)., PMID:12153520
• Thrombospondin-bound integrin-associated protein (CD47) physically and functionally modifies integrin alphaIIbbeta3 by its extracellular domain., PMID:12736272
• The thrombospondin receptor integrin-associated protein (CD47) functionally couples to heterotrimeric Gi., PMID:10085089
