U-Blot® Research Grade Samrotamab
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$9,999.00
Product details
Background：Samrotamab is a humanized IgG1-κ chimeric antibody targeting LRRC15.
• A novel member of the leucine-rich repeat superfamily induced in rat astrocytes by beta-amyloid., PMID:11785964
• Mediators of inflammation and regeneration., PMID:21677081
• Lib, transcriptionally induced in senile plaque-associated astrocytes, promotes glial migration through extracellular matrix., PMID:16098915
• High lib mRNA expression in breast carcinomas., PMID:15368894
Specifications
| Target | Leucine-rich repeat protein induced by beta-amyloid homolog |
| Reactivity | Human |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Humanized |
| Isotype | IgG1-kappa |
| Conjugate/Modification | |
| Modification | |
| Recommended Dilution Ratio | |
| Composition | 0.01M PBS, pH 7.4. |
| Purification Process | Protein A/G purified from cell culture supernatant. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Storage Condition | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | |
| Immunogen | Mammalian Cells |
| Gene Name | |
| Protein Name | |
| Alias | Leucine-rich repeat protein induced by beta-amyloid homolog, LRRC15, Leucine-rich repeat-containing protein 15, LIB, hLib |
| Species | |
| Gene ID-1 | Q8TF66 |
| Uniprot | |
| Species.1 | |
| Gene ID | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.1 | |
| Uniprot.2 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Description | Background：Samrotamab is a humanized IgG1-κ chimeric antibody targeting LRRC15.<br>• A novel member of the leucine-rich repeat superfamily induced in rat astrocytes by beta-amyloid., PMID:11785964<br />• Mediators of inflammation and regeneration., PMID:21677081<br />• Lib, transcriptionally induced in senile plaque-associated astrocytes, promotes glial migration through extracellular matrix., PMID:16098915<br />• High lib mRNA expression in breast carcinomas., PMID:15368894<br /> |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function |
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