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Home/Reagents/Antibody/Biosimilar & Bispecific Antibodies/U-Blot® Research Grade Urtoxazumab
SKU: WA3735 Categories: ,

U-Blot® Research Grade Urtoxazumab

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$9,999.00

SKU: WA3735-50
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Product details

Background：Urtoxazumab (TMA-15) is a humanizedized monoclonal antibody against Shiga toxin (Stx) 2.
• Shiga Toxin (Stx) Classification, Structure, and Function., PMID:25530917
• Shiga-toxin-converting bacteriophages., PMID:11686382
• Escherichia albertii Pathogenesis., PMID:32588811
• Shiga Toxin-Producing Escherichia coli Infections during Pregnancy., PMID:30360505
• Switching Shiga Toxin (Stx) Type from Stx2d to Stx2a but Not Stx2c Alters Virulence of Stx-Producing Escherichia coli (STEC) Strain B2F1 in Streptomycin (Str)-Treated Mice., PMID:33467588
• Targeting bacterial toxins., PMID:22441768
• Shiga toxin-induced haemolytic uraemic syndrome and the role of antibiotics: a global overview., PMID:31150744
• L-Arabinose inhibits Shiga toxin type 2-converting bacteriophage induction in Escherichia coli O157:H7., PMID:37332116
• Shiga toxin 2a and Enteroaggregative Escherichia coli–a deadly combination., PMID:26039753
• Shiga Toxin (Stx) Type 1a and Stx2a Translocate through a Three-Layer Intestinal Model., PMID:36977098

Specifications

Targetshiga toxin type 2stx2B
ReactivityEscherichia coli
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
MW(Calculated)
MW(Observed)
Host SpeciesHumanized
IsotypeIgG1-kappa
Conjugate/Modification
Modification
Recommended Dilution Ratio
Composition0.01M PBS, pH 7.4.
Purification ProcessProtein A/G purified from cell culture supernatant.
Purity>95% purity as determined by SDS-PAGE.
Storage ConditionUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Concentration
ClonalityMonoclonal
Clone Number
ImmunogenMammalian Cells
Gene Name
Protein Name
Aliasshiga toxin type 2stx2B
Species
Gene ID-1Q07871
Uniprot
Species.1
Gene ID
Uniprot.1
Species.2
Gene ID.1
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
DescriptionBackground：Urtoxazumab (TMA-15) is a humanizedized monoclonal antibody against Shiga toxin (Stx) 2.<br>• Shiga Toxin (Stx) Classification, Structure, and Function., PMID:25530917<br />• Shiga-toxin-converting bacteriophages., PMID:11686382<br />• <i>Escherichia albertii</i> Pathogenesis., PMID:32588811<br />• Shiga Toxin-Producing <i>Escherichia coli</i> Infections during Pregnancy., PMID:30360505<br />• Switching Shiga Toxin (Stx) Type from Stx2d to Stx2a but Not Stx2c Alters Virulence of Stx-Producing <i>Escherichia coli</i> (STEC) Strain B2F1 in Streptomycin (Str)-Treated Mice., PMID:33467588<br />• Targeting bacterial toxins., PMID:22441768<br />• Shiga toxin-induced haemolytic uraemic syndrome and the role of antibiotics: a global overview., PMID:31150744<br />• L-Arabinose inhibits Shiga toxin type 2-converting bacteriophage induction in <i>Escherichia coli</i> O157:H7., PMID:37332116<br />• Shiga toxin 2a and Enteroaggregative Escherichia coli--a deadly combination., PMID:26039753<br />• Shiga Toxin (Stx) Type 1a and Stx2a Translocate through a Three-Layer Intestinal Model., PMID:36977098<br />
Cellular Localization
Tissue Expression
Signaling_pathway
Research Areas
Function
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