U-Blot® RNA Pol II CTD phospho Thr4 Monoclonal Antibody
UcallM
$999.00
Product details
Background:Genome-wide profiling revealed high levels of K7me1/2 marks at the transcriptional start site of genes for sense and antisense transcribing RNAPII. The new K7 modifications further expand the mammalian CTD code to allow regulation of differential gene expression. In analogy, it appears likely that the various modifications of K7 residues identified in this analysis may similarly contribute to fine tuning of gene expressing by RNAPII, and that these modifications are placed in K7 residues of CTD dependent on cell signaling and epigenetic programming of cells.
Specifications
| Target | -- |
| Reactivity | Human, Wide Range Predicted |
| Applications | ChIP; WB; IP; IF; DB; ELISA; ICC |
| MW(Calculated) | 240 kDa |
| Host Species | Rat |
| Isotype | IgG2b |
| Recommended Dilution Ratio | Applications Validated by Active Motif: WB: 0.5 - 2 µg/ml DB: 1 µg/ml |
| Formulation | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
| Purification | Protein G Chromatography |
| Storage | Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage. |
| Concentration | -- |
| Clonality | Monoclonal |
| Clone Number | 6D7 |
| Immunogen | This antibody was raised against a synthetic peptide corresponding to RNA Pol II CTD phosphorylated at threonine 4. |
| Specificity | -- |
| Gene Name | -- |
| Other Name | RPB1, RPO2, POLR2, POLRA, RPBh1, RPOL2, RpIILS, hsRPB1, hRPB220 |
| Gene ID | -- |
| Cellular Localization | -- |
| Function | -- |
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