Specifications
| Size | 50μL/100μL |
| Target | RRM2 |
| Reactivity | Human |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 45kD |
| MW(Observed) | 50kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1544R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | RRM2 RR2 |
| Protein Name | Ribonucleoside-diphosphate reductase subunit M2 |
| Other Name | RIR2; / Ribonucleoside-diphosphate reductase subunit M2; / Ribonucleotide reductase small chain; / Ribonucleotide reductase small subunit |
| Species | Human |
| Gene ID | 6241 |
| Uniprot | P31350, |
| Species.1 | Mouse |
| Gene ID.1 | 20135 |
| Uniprot.1 | P11157, |
| Species.2 | Rat |
| Gene ID.2 | 20135 |
| Uniprot.2 | Q4KLN6 |
| Cellular Localization | Cytoplasm . Nucleus . Localized to the cytoplasm in S phase cells. May localize to the nucleus in G2 phase cells. . |
| Tissue Expression | |
| Signaling_pathway | Cellular Processes >> Cell growth and death >> p53 signaling pathway |
| Research Areas | >>Purine metabolism; / >>Pyrimidine metabolism; / >>Glutathione metabolism; / >>Drug metabolism - other enzymes; / >>Metabolic pathways; / >>Nucleotide metabolism; / >>p53 signaling pathway |
| Function |
