Specifications
| Size | 50μL/100μL |
| Target | S100P |
| Reactivity | Human |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 10kD |
| MW(Observed) | 10kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:200-1:1000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1648R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | S100P S100E |
| Protein Name | Protein S100-P |
| Other Name | S100P; / S100E; / Protein S100-P; / Protein S100-E; / S100 calcium-binding protein P |
| Species | Human |
| Gene ID | 6286 |
| Uniprot | P25815 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus. Cytoplasm. Cell projection, microvillus membrane. Colocalizes with S100PBP in the nucleus. Colocolizes with EZR in the microvilli in a calcium-dependent manner. |
| Tissue Expression | Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias. |
| Signaling_pathway | |
| Research Areas | |
| Function | miscellaneous:This protein binds two calcium ions.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subcellular location:Colocalizes with S100PBP in the nucleus.,subunit:Homodimer. Interacts with S100PBP and S100Z.,tissue specificity:Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias., |
