U-Blot® SLC2A8 Rabbit mAb
Ucallm_WR5913-50
Price range: $268.00 through $328.00
Product details
Background：
This gene belongs to the solute carrier 2A family , which includes intracellular glucose transporters. Based on sequence comparison , the glucose transporters are grouped into three classes and this gene is a member of class II. The encoded protein , like other members of the family , contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq , Nov 2012] ,
Specifications
| Size | 50μL/100μL |
| Target | SLC2A8 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IF, ELISA |
| MW(Calculated) | 51kD |
| MW(Observed) | 38kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1894R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | SLC2A8 GLUT8 GLUTX1 |
| Protein Name | Solute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (GLUT-8) (Glucose transporter type X1) |
| Other Name | |
| Species | Human |
| Gene ID | 29988 |
| Uniprot | Q9NY64, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9JIF3, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q9JJZ1 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . Cytoplasmic vesicle membrane; Multi-pass membrane protein . Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration. . |
| Tissue Expression | Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose.,induction:In testis, down-regulated by estrogen.,similarity:Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.,subcellular location:Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration.,tissue specificity:Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues., |
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