SKU: WR5022 Categories: ,

U-Blot® SOX1 Rabbit mAb

Price range: $268.00 through $328.00

SKU: WR5022-100
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Product details

Background:SRY-box 1(SOX1) Homo sapiens This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetSOX1
ReactivityHuman, Mouse, Rat
ApplicationsWB, IF, ELISA
MW(Calculated)39kD
MW(Observed)45kD
Host SpeciesRabbit
IsotypeIgG,Kappa
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:5000-1:20000;
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
PurificationRecombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberRM1254R
ImmunogenThe specific immunogen used to produce this antibody is proprietary information.
SpecificityEndogenous
Gene NameSOX1
Protein NameTranscription factor SOX-1
Other Name
SpeciesHuman
Gene ID6656
UniprotO00570,
Species.1Mouse
Gene ID.1
Uniprot.1P53783
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus .
Tissue ExpressionMainly expressed in the developing central nervous system.
Signaling_pathway
Research Areas
FunctionFunction:Transcriptional activator.,similarity:Contains 1 HMG box DNA-binding domain.,tissue specificity:Mainly in the developing central nervous system.,
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