IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality
Monoclonal
Clone Number
RM1906R
Immunogen
The specific immunogen used to produce this antibody is proprietary information.
Specificity
Endogenous
Gene Name
SQLE ERG1
Protein Name
Squalene monooxygenase (Squalene epoxidase) (SE)
Other Name
Species
Human
Gene ID
6713
Uniprot
Q14534,
Species.1
Mouse
Gene ID.1
20775
Uniprot.1
P52019,
Species.2
Rat
Gene ID.2
29230
Uniprot.2
P52020
Cellular Localization
Microsome membrane; Peripheral membrane protein . Endoplasmic reticulum membrane; Peripheral membrane protein .
Tissue Expression
Detected in liver (at protein level).
Signaling_pathway
Research Areas
Function
Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.