U-Blot® SQLE Rabbit mAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | SQLE |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | 64kD |
| MW(Observed) | 64kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1906R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | SQLE ERG1 |
| Protein Name | Squalene monooxygenase (Squalene epoxidase) (SE) |
| Other Name | |
| Species | Human |
| Gene ID | 6713 |
| Uniprot | Q14534, |
| Species.1 | Mouse |
| Gene ID.1 | 20775 |
| Uniprot.1 | P52019, |
| Species.2 | Rat |
| Gene ID.2 | 29230 |
| Uniprot.2 | P52020 |
| Cellular Localization | Microsome membrane; Peripheral membrane protein . Endoplasmic reticulum membrane; Peripheral membrane protein . |
| Tissue Expression | Detected in liver (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis. |
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