U-Blot® Trop2 hIgG1 Reference Antibody (Sacbio)
Product details
Background:TROP2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.
Specifications
| Target | Trop2 |
| Reactivity | |
| Applications | Flow cytometry |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Human |
| Isotype | IgG1 |
| Conjugate/Modification | Unconjugated |
| Modification | |
| Recommended Dilution Ratio | |
| Formulation Buffer | Phosphate-buffered solution, pH 7.2-7.4. |
| Source | |
| Purification | |
| Purity | > 95% as determined by SDS-PAGE |
| Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -408℃ long term.Avoid repeated freeze-thaw. |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | Sacituzumab |
| Immunogen | |
| Sequence | |
| Specificity | |
| Gene Name | |
| Protein Name | |
| Other Name | EGP-1, EGP1, GA733-1, GA7331, GP50, M1S1, TACSTD2 |
| Species | |
| Gene ID | |
| Uniprot | |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Organism-4 | |
| GeneID-4 | |
| SwissProt-4 | |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | |
| RRID |
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