U-Blot® XBP-1s Antibody
Specifications
| Target | XBP-1s |
| Reactivity | Human, Mouse |
| Applications | WB,ICC, ChIP, |
| MW(Calculated) | -- |
| Host Species | Mouse |
| Isotype | Mouse IgG2a, κ |
| Recommended Dilution Ratio | Each lot of this antibody is quality control tested by Western blotting . For Western blotting, the suggested use of this reagent is 0.5 - 2.0 µg per mL. For ChIP application, use 2 µg of antibody and 10 µg of chromatin per IP. It is recommended that the reagent be titrated for optimal performance for each application. |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Purification | The antibody was purified by affinity chromatography. |
| Storage | The antibody solution should be stored undiluted between 2°C and 8°C. |
| Concentration | 0.5 mg/ml |
| Clonality | Monoclonal |
| Clone Number | RMM11A4 |
| Immunogen | Partial mouse XBP-1s recombinant protein (162-267aa) |
| Specificity | XBP-1s |
| Gene Name | -- |
| Other Name | XBP-1 isoform2, Tax-responsive element-binding protein 5 (TREB5), XBP2 |
| Gene ID | 7494 |
| Cellular Localization | MHC Antigens, Nuclear Markers |
| Function | Upregulated by ER stress, IL-6, and IL-4. Downregulation correlates with tumor progression in prostate cancer. Downregulated by PAX5 transcription factor. |
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