SKU: WP7508 Categories: ,

UBE2F rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7508-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetUBE2F
ReactivityHuman, Rat
ApplicationsWB
MW(Calculated)20kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human UBE2F
SpecificityThis antibody detects endogenous levels of UBE2F at Human,Rat
Gene NameUBE2F NCE2
Protein NameNEDD8-conjugating enzyme UBE2F (NEDD8 carrier protein UBE2F) (NEDD8 protein ligase UBE2F) (NEDD8-conjugating enzyme 2) (Ubiquitin-conjugating enzyme E2 F)
Other Name
SpeciesHuman
Gene ID140739
UniprotQ969M7,
Species.1
Gene ID.1
Uniprot.1
Species.2Rat
Gene ID.2363284
Uniprot.2Q5U203
Cellular Localization
Tissue ExpressionWidely expressed (at protein level).
Signaling_pathwayGenetic Information Processing >> Folding, sorting and degradation >> Ubiquitin mediated proteolysis
Research Areas
FunctionAccepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
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