Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human UBR3 AA range: 1591-1641
Specificity
This antibody detects endogenous levels of UBR3 at Human/Mouse
Gene Name
UBR3 KIAA2024 ZNF650
Protein Name
UBR3
Other Name
Species
Human
Gene ID
130507
Uniprot
Q6ZT12,
Species.1
Mouse
Gene ID.1
68795
Uniprot.1
Q5U430
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Membrane; Multi-pass membrane protein .
Tissue Expression
Signaling_pathway
Research Areas
Function
Function:E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Does not bind to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.,pathway:Protein modification; protein ubiquitination.,sequence Caution:Translated as Gln.,similarity:Belongs to the UBR1 family.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 1 UBR-type zinc finger.,subunit:Interacts with UBE2A and UBE2B.,