SKU: WP4022 Categories: ,

UBR3 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP4022-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetUBR3
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)208kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human UBR3 AA range: 1591-1641
SpecificityThis antibody detects endogenous levels of UBR3 at Human/Mouse
Gene NameUBR3 KIAA2024 ZNF650
Protein NameUBR3
Other Name
SpeciesHuman
Gene ID130507
UniprotQ6ZT12,
Species.1Mouse
Gene ID.168795
Uniprot.1Q5U430
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationMembrane; Multi-pass membrane protein .
Tissue Expression
Signaling_pathway
Research Areas
FunctionFunction:E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Does not bind to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.,pathway:Protein modification; protein ubiquitination.,sequence Caution:Translated as Gln.,similarity:Belongs to the UBR1 family.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 1 UBR-type zinc finger.,subunit:Interacts with UBE2A and UBE2B.,
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