Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human UBXN1 AA range: 56-106
Specificity
This antibody detects endogenous levels of UBXN1 at Human/Mouse/Rat
Gene Name
UBXN1 SAKS1
Protein Name
UBXN1
Other Name
Species
Human
Gene ID
51035
Uniprot
Q04323,
Species.1
Mouse
Gene ID.1
225896
Uniprot.1
Q922Y1,
Species.2
Rat
Gene ID.2
Uniprot.2
Q499N6
Cellular Localization
Cytoplasm .
Tissue Expression
Signaling_pathway
Genetic Information Processing >> Folding, sorting and degradation >> Protein processing in endoplasmic reticulum
Research Areas
>>Protein processing in endoplasmic reticulum
Function
Function:Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol. Involved in ubiquitin-proteasome systems.,similarity:Contains 1 UBA domain.,similarity:Contains 1 UBX domain.,subunit:Component of a complex required to couple retrotranslocation, ubiquitination and deglycosylation composed of NGLY1, SAKS1, AMFR, VCP and RAD23B. Interacts with HOMER2 (By similarity). Interacts directly with VCP. Binds polyubiquitin.,