SKU: WP14935 Categories: ,

UEV3 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14935-100
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Product details

Background:

function:Possible negative regulator of polyubiquitination., similarity:Contains 1 UEV (ubiquitin E2 variant) domain., similarity:In the C-terminal section; belongs to the LDH/MDH superfamily., similarity:In the N-terminal section; belongs to the ubiquitin-conjugating enzyme family. UEV subfamily., subunit:Homodimer., tissue specificity:Colon, colon carcinoma cell lines, normal cervical epithelium, carcinomas of the uterine cervix and peripheral blood leukocytes.,

Specifications

TargetUEV3
ReactivityHuman, Mouse
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)52kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human UEVLD. AA range:141-190
Sequence
SpecificityUEV3 Polyclonal Antibody detects endogenous levels of UEV3 protein.
Gene NameUEVLD
Protein NameUbiquitin-conjugating enzyme E2 variant 3
Other NameUEVLD; / UEV3; / Ubiquitin-conjugating enzyme E2 variant 3; / UEV-3; / EV and lactate/malate dehydrogenase domain-containing protein
SpeciesHuman
Gene ID-155293
UniprotQ8IX04,
Species.1Mouse
Gene ID-2
Uniprot.1Q3U1V6
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Backgroundfunction:Possible negative regulator of polyubiquitination.,similarity:Contains 1 UEV (ubiquitin E2 variant) domain.,similarity:In the C-terminal section; belongs to the LDH/MDH superfamily.,similarity:In the N-terminal section; belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.,subunit:Homodimer.,tissue specificity:Colon, colon carcinoma cell lines, normal cervical epithelium, carcinomas of the uterine cervix and peripheral blood leukocytes.,
Cellular Localizationextracellular exosome,
Tissue ExpressionColon, colon carcinoma cell lines, normal cervical epithelium, carcinomas of the uterine cervix and peripheral blood leukocytes.
Signaling_pathway
Research Areas
FunctionFunction:Possible negative regulator of polyubiquitination.,similarity:Contains 1 UEV (ubiquitin E2 variant) domain.,similarity:In the C-terminal section; belongs to the LDH/MDH superfamily.,similarity:In the N-terminal section; belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.,subunit:Homodimer.,tissue specificity:Colon, colon carcinoma cell lines, normal cervical epithelium, carcinomas of the uterine cervix and peripheral blood leukocytes.,
RRID
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