SKU: WP6425 Categories: ,

UGCGL1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6425-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetUGGT1
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)171kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human UGCGL1
SpecificityThis antibody detects endogenous levels of UGCGL1 at Human, Mouse,Rat
Gene NameUGGT1 GT UGCGL1 UGGT UGT1 UGTR
Protein NameUDP-glucose:glycoprotein glucosyltransferase 1 (UGT1) (hUGT1) (UDP--Glc:glycoprotein glucosyltransferase) (UDP-glucose ceramide glucosyltransferase-like 1)
Other Name
SpeciesHuman
Gene ID56886
UniprotQ9NYU2,
Species.1Mouse
Gene ID.1320011
Uniprot.1Q6P5E4,
Species.2Rat
Gene ID.2171129
Uniprot.2Q9JLA3
Cellular LocalizationEndoplasmic reticulum lumen . Endoplasmic reticulum-Golgi intermediate compartment .
Tissue ExpressionHigher levels in pancreas, skeletal muscle, kidney, and brain. Low levels in lung and heart.
Signaling_pathwayGenetic Information Processing >> Folding, sorting and degradation >> Protein processing in endoplasmic reticulum
Research Areas
FunctionRecognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
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