UGCGL1 rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | UGGT1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 171kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human UGCGL1 |
| Specificity | This antibody detects endogenous levels of UGCGL1 at Human, Mouse,Rat |
| Gene Name | UGGT1 GT UGCGL1 UGGT UGT1 UGTR |
| Protein Name | UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1) (hUGT1) (UDP--Glc:glycoprotein glucosyltransferase) (UDP-glucose ceramide glucosyltransferase-like 1) |
| Other Name | |
| Species | Human |
| Gene ID | 56886 |
| Uniprot | Q9NYU2, |
| Species.1 | Mouse |
| Gene ID.1 | 320011 |
| Uniprot.1 | Q6P5E4, |
| Species.2 | Rat |
| Gene ID.2 | 171129 |
| Uniprot.2 | Q9JLA3 |
| Cellular Localization | Endoplasmic reticulum lumen . Endoplasmic reticulum-Golgi intermediate compartment . |
| Tissue Expression | Higher levels in pancreas, skeletal muscle, kidney, and brain. Low levels in lung and heart. |
| Signaling_pathway | Genetic Information Processing >> Folding, sorting and degradation >> Protein processing in endoplasmic reticulum |
| Research Areas | |
| Function | Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation. |
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