Product details
Background:
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UPP2 rabbit pAb
Ucallm_WP3958-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | UPP2 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 35kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human UPP2 AA range: 164-214 |
| Specificity | This antibody detects endogenous levels of UPP2 at Human/Mouse |
| Gene Name | UPP2 |
| Protein Name | UPP2 |
| Other Name | |
| Species | Human |
| Gene ID | 151531 |
| Uniprot | O95045, |
| Species.1 | Mouse |
| Gene ID.1 | 76654 |
| Uniprot.1 | Q8CGR7 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | cytoplasm,cytosol,type III intermediate filament, |
| Tissue Expression | Predominantly expressed in kidney. |
| Signaling_pathway | |
| Research Areas | >>Pyrimidine metabolism; / >>Drug metabolism - other enzymes; / >>Metabolic pathways; / >>Nucleotide metabolism |
| Function | Catalytic activity:Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.,Function:Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.,pathway:Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from uridine (phosphorylase route): step 1/1.,similarity:Belongs to the PNP/UDP phosphorylase family.,tissue specificity:Predominantly expressed in kidney., |
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