Product details
Background:
The protein encoded by this gene is a deubiquitinase involved in the DNA damage pathway and DNA damage-induced apoptosis. Overexpression of this gene is seen in several cancers. [provided by RefSeq, Oct 2016],
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USP28 Polyclonal Antibody
Ucallm_WP0481-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | UBP28 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 118kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 650-730 |
| Specificity | UBP28 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | USP28 KIAA1515 |
| Protein Name | Ubiquitin carboxyl-terminal hydrolase 28 (Deubiquitinating enzyme 28) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) |
| Other Name | |
| Species | Human |
| Gene ID | 57646 |
| Uniprot | Q96RU2, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q5I043, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | D3ZJ96 |
| Cellular Localization | Nucleus, nucleoplasm . |
| Tissue Expression | Brain,Eye, |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 UIM (ubiquitin-interacting motif) repeat., |
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