USP36 Polyclonal Antibody
Ucallm_WP14953-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a member of the peptidase C19 or ubiquitin-specific protease family of cysteine proteases. Members of this family remove ubiquitin molecules from polyubiquitinated proteins. The encoded protein may deubiquitinate and stabilize the transcription factor c-Myc, also known as MYC, an important oncoprotein known to be upregulated in most human cancers. The encoded protease may also regulate the activation of autophagy. This gene exhibits elevated expression in some breast and lung cancers. [provided by RefSeq, Mar 2016],
Specifications
| Size | 50μL/100μL |
| Target | USP36 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 125kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human USP36. AA range:501-550 |
| Specificity | USP36 Polyclonal Antibody detects endogenous levels of USP36 protein. |
| Gene Name | USP36 |
| Protein Name | Ubiquitin carboxyl-terminal hydrolase 36 |
| Other Name | USP36; / KIAA1453; / Ubiquitin carboxyl-terminal hydrolase 36; / Deubiquitinating enzyme 36; / Ubiquitin thioesterase 36; / Ubiquitin-specific-processing protease 36 |
| Species | Human |
| Gene ID | 57602 |
| Uniprot | Q9P275, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | B1AQJ2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus, nucleolus . Cytoplasm . |
| Tissue Expression | Broadly expressed. |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Broadly expressed., |
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