Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human VA0E2 AA range: 26-75
Specificity
This antibody detects endogenous levels of human VA0E2
Gene Name
ATP6V0E2 ATP6V0E2L C7orf32
Protein Name
V-type proton ATPase subunit e 2 (V-ATPase subunit e 2) (Lysosomal 9 kDa H(+)-transporting ATPase V0 subunit e2) (Vacuolar proton pump subunit e 2)
Other Name
Species
Human
Gene ID
155066
Uniprot
Q8NHE4,
Species.1
Mouse
Gene ID.1
76252
Uniprot.1
Q91XE7,
Species.2
Rat
Gene ID.2
76252
Uniprot.2
Q5EB76
Cellular Localization
Membrane; Multi-pass membrane protein . Cytoplasmic vesicle, clathrin-coated vesicle membrane; Multi-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein .
Tissue Expression
Isoform 1 is expressed at high levels in heart, brain and kidney and also detected in inner ear epithelium, vestibule, testis, epididymis and bladder. Isoform 2 is expressed in heart, kidney, placenta and pancreas. Isoform 2 is not detected in frontal cortex, but is prevalent in all other brain areas.
Signaling_pathway
Cellular Processes >> Transport and catabolism >> Phagosome;Organismal Systems >> Nervous system >> Synaptic vesicle cycle;Human Diseases >> Immune disease >> Rheumatoid arthritis