Name: U-Blot® VGLUT1 Rabbit mAb
SKU: WR4941
Price: 268 USD
Availability: InStock

U-Blot® VGLUT1 Rabbit mAb

Ucallm_WR4941-50

Price range: $268.00 through $328.00

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50μl

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SKU: WR4941-50

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Product details

Background:The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family. [provided by RefSeq, Jul 2008],

Specifications

Size	50μL/100μL
Target	VGLUT1
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, IP, ELISA
MW(Calculated)	62kD
MW(Observed)	62kD
Host Species	Rabbit
Isotype	IgG,Kappa
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification	Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	RM1164R
Immunogen	The specific immunogen used to produce this antibody is proprietary information.
Specificity	Endogenous
Gene Name	SLC17A7 BNPI VGLUT1
Protein Name	Vesicular glutamate transporter 1
Other Name	VGLU1; / Vesicular glutamate transporter 1; / VGluT1; / Brain-specific Na; / +; / -dependent inorganic phosphate cotransporter; / Solute carrier family 17 member 7
Species	Human
Gene ID	57030
Uniprot	Q9P2U7,
Species.1	Mouse
Gene ID.1	72961
Uniprot.1	Q3TXX4,
Species.2	Rat
Gene ID.2	116638
Uniprot.2	Q62634
Cellular Localization	Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane . Membrane; Multi-pass membrane protein . Cell junction, synapse, synaptosome .
Tissue Expression	Expressed in several regions of the brain including amygdala, cerebellum, cerebral cortex, hippocampus, frontal lobe, medulla, occipital lobe, putamen and temporal lobe.
Signaling_pathway	Organismal Systems >> Nervous system >> Glutamatergic synapse;Organismal Systems >> Nervous system >> Synaptic vesicle cycle
Research Areas	>>Synaptic vesicle cycle; / >>Retrograde endocannabinoid signaling; / >>Glutamatergic synapse; / >>Nicotine addiction
Function	Function:Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.,similarity:Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.,tissue specificity:Expressed in several regions of the brain including amygdala, cerebellum, cerebral cortex, hippocampus, frontal lobe, medulla, occipital lobe, putamen and temporal lobe.,