Name: VPS18 rabbit pAb
SKU: WP4170
Price: 268 USD
Availability: InStock

VPS18 rabbit pAb

Ucallm_WP4170-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WP4170-100

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Product details

Background:

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps18 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. [provided by RefSeq, Jul 2008],

Specifications

Size	50μL/100μL
Target	VPS18
Reactivity	Human, Mouse
Applications	WB
MW(Calculated)	107kD
MW(Observed)
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human VPS18 AA range: 778-828
Specificity	This antibody detects endogenous levels of VPS18 at Human/Mouse
Gene Name	VPS18 KIAA1475
Protein Name	VPS18
Other Name
Species	Human
Gene ID	57617
Uniprot	Q9P253,
Species.1	Mouse
Gene ID.1	228545
Uniprot.1	Q8R307
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Late endosome membrane; Peripheral membrane protein; Cytoplasmic side . Lysosome membrane; Peripheral membrane protein; Cytoplasmic side . Early endosome . Cytoplasmic vesicle, autophagosome . Cytoplasmic vesicle, clathrin-coated vesicle . Cytoplasmic, peripheral membrane protein associated with early endosomes and late endosomes/lysosomes.
Tissue Expression	Ubiquitous. Expression was highest in heart and low in lung.
Signaling_pathway	Cellular Processes >> Transport and catabolism >> Autophagy - animal
Research Areas	>>Salmonella infection
Function	Function:May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes.,similarity:Belongs to the VPS18 family.,similarity:Contains 1 clathrin repeat.,similarity:Contains 1 RING-type zinc finger.,subcellular location:Cytoplasmic, peripheral membrane protein associated with late endosomes/lysosomes.,subunit:Interacts with HOOK1 (By similarity). Large hetero-oligomeric complex together with VPS11, VPS16 and VPS33A. Interacts with STX7.,tissue specificity:Ubiquitous. Expression was highest in heart and low in lung.,

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VPS18 rabbit pAb

Product details

Specifications

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VPS18 rabbit pAb

Product details

Specifications

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