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Home/Reagents/Antibody/Primary antibody/Polyclonal Antibody/Rabbit pAb/VPS26B Polyclonal Antibody
SKU: WP15001 Categories: ,

VPS26B Polyclonal Antibody

Ucallm_WP15001-50

Price range: $268.00 through $328.00

SKU: WP15001-100
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Product details

Background:

function:Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the VPS26 family., subcellular location:Does not localize to endosomes., subunit:Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.,

Specifications

Size50μL/100μL
TargetVPS26B
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)45kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human VPS26B. AA range:231-280
SpecificityVPS26B Polyclonal Antibody detects endogenous levels of VPS26B protein.
Gene NameVPS26B
Protein NameVacuolar protein sorting-associated protein 26B
Other NameVPS26B; / Vacuolar protein sorting-associated protein 26B; / Vesicle protein sorting 26B
SpeciesHuman
Gene ID112936
UniprotQ4G0F5,
Species.1Mouse
Gene ID.169091
Uniprot.1Q8C0E2
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm . Membrane; Peripheral membrane protein . Early endosome . Late endosome . Localizes to early and late endosomal structures (By similarity). .
Tissue ExpressionEye,Lung,Placenta,
Signaling_pathway
Research Areas>>Endocytosis
FunctionFunction:Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the VPS26 family.,subcellular location:Does not localize to endosomes.,subunit:Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.,
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