VPS26B Polyclonal Antibody
Ucallm_WP15001-50
Price range: $268.00 through $328.00
Product details
Background:
function:Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the VPS26 family., subcellular location:Does not localize to endosomes., subunit:Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.,
Specifications
| Size | 50μL/100μL |
| Target | VPS26B |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 45kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human VPS26B. AA range:231-280 |
| Specificity | VPS26B Polyclonal Antibody detects endogenous levels of VPS26B protein. |
| Gene Name | VPS26B |
| Protein Name | Vacuolar protein sorting-associated protein 26B |
| Other Name | VPS26B; / Vacuolar protein sorting-associated protein 26B; / Vesicle protein sorting 26B |
| Species | Human |
| Gene ID | 112936 |
| Uniprot | Q4G0F5, |
| Species.1 | Mouse |
| Gene ID.1 | 69091 |
| Uniprot.1 | Q8C0E2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Membrane; Peripheral membrane protein . Early endosome . Late endosome . Localizes to early and late endosomal structures (By similarity). . |
| Tissue Expression | Eye,Lung,Placenta, |
| Signaling_pathway | |
| Research Areas | >>Endocytosis |
| Function | Function:Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the VPS26 family.,subcellular location:Does not localize to endosomes.,subunit:Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35., |
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