SKU: WP2714 Categories: ,

WASL Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP2714-100
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Product details

Background:

This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension. [provided by RefSeq, Jul 2013],

Specifications

TargetWASL
ReactivityHuman, Rat, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)55kD
Host SpeciesRabbit
IsotypeIgG
Conjugate
ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000;ELISA 1:5000-20000
CompositionLiquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Purification ProcessThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage Condition-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 190-270
Sequence
SpecificityWASL Polyclonal Antibody detects endogenous levels of protein.
Gene NameWASL
Protein NameNeural Wiskott-Aldrich syndrome protein (N-WASP)
Alias
Organism-1Human
Gene ID-18976
SwissProt-1O00401
Organism-2Mouse
Gene ID-2
SwissProt-2Q91YD9
Organism-3Rat
Gene ID-3
SwissProt-3O08816
Organism-4
Gene ID-4
SwissProt-4
Cellular LocalizationCytoplasm, cytoskeleton . Nucleus . Cytoplasm . Preferentially localized in the cytoplasm when phosphorylated and in the nucleus when unphosphorylated (By similarity). Exported from the nucleus by an nuclear export signal (NES)-dependent mechanism to the cytoplasm (By similarity). .
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