WBP2 rabbit pAb
Ucallm_WP6401-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | WBP2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 29kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human WBP2 |
| Specificity | This antibody detects endogenous levels of WBP2 at Human, Mouse,Rat |
| Gene Name | WBP2 |
| Protein Name | WW domain-binding protein 2 (WBP-2) |
| Other Name | |
| Species | Human |
| Gene ID | 23558 |
| Uniprot | Q969T9, |
| Species.1 | Mouse |
| Gene ID.1 | 22378 |
| Uniprot.1 | P97765, |
| Species.2 | Rat |
| Gene ID.2 | 192645 |
| Uniprot.2 | Q8R478 |
| Cellular Localization | Cytoplasm . Nucleus . Translocates from cytoplasm to nucleus when phosphorylated. . |
| Tissue Expression | Ubiquitous. |
| Signaling_pathway | |
| Research Areas | |
| Function | Acts as transcriptional coactivator of estrogen and progesterone receptors (ESR1 and PGR) upon hormone activation . In presence of estrogen, binds to ESR1-responsive promoters . Required for YAP1 coactivation function on PGR activity . Synergizes with WBP2 in enhancing PGR activity . Modulates expression of post-synaptic scaffolding proteins via regulation of ESR1, ESR2 and PGR (By similarity). |
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