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WDHD1 Polyclonal Antibody
Ucallm_WP15014-50
Price range: $268.00 through $328.00
Product details
Background:
The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | WDHD1 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 126kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human WDHD1. AA range:721-770 |
| Specificity | WDHD1 Polyclonal Antibody detects endogenous levels of WDHD1 protein. |
| Gene Name | WDHD1 |
| Protein Name | WD repeat and HMG-box DNA-binding protein 1 |
| Other Name | WDHD1; / AND1; / WD repeat and HMG-box DNA-binding protein 1; / Acidic nucleoplasmic DNA-binding protein 1; / And-1 |
| Species | Human |
| Gene ID | 11169 |
| Uniprot | O75717, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P59328 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus, nucleoplasm . |
| Tissue Expression | Embryonal rhabdomyosarcoma,Epithelium,Fetal brain,Liver,Ski |
| Signaling_pathway | |
| Research Areas | |
| Function | Caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,Function:Binds DNA with high affinity. May also be involved in protein-protein interactions.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 HMG box DNA-binding domain.,similarity:Contains 7 WD repeats., |
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