WDR1 rabbit pAb
Ucallm_WP6209-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | WDR1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 67kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human WDR1 |
| Specificity | This antibody detects endogenous levels of WDR1 at Human, Mouse,Rat |
| Gene Name | WDR1 |
| Protein Name | WD repeat-containing protein 1 (Actin-interacting protein 1) (AIP1) (NORI-1) |
| Other Name | |
| Species | Human |
| Gene ID | 9948 |
| Uniprot | O75083, |
| Species.1 | Mouse |
| Gene ID.1 | 22388 |
| Uniprot.1 | O88342, |
| Species.2 | Rat |
| Gene ID.2 | 360950 |
| Uniprot.2 | Q5RKI0 |
| Cellular Localization | Cytoplasm . Cytoplasm, cytoskeleton . Cell projection, podosome . Cell junction . |
| Tissue Expression | Expressed in peripheral blood mononuclear cells (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins . Enhances cofilin-mediated actin severing (By similarity). Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions . Involved in myocardium sarcomere organization. Required for cardiomyocyte growth and maintenance (By similarity). Involved in megakaryocyte maturation and platelet shedding. Required for the establishment of planar cell polarity (PCP) during follicular epithelium development and for cell shape changes during PCP; the function seems to implicate cooperation with CFL1 and/or DSTN/ADF. Involved in the generation/maintenance of cortical tension (By similarity). Involved in assembly and maintenance of epithelial apical cell junctions and plays a role in the organization of the perijunctional actomyosin belt . |
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