Product details
Background:
WDR19/IFT144 rabbit pAb
Ucallm_WP6311-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | WDR19 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 148kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human WDR19/IFT144 |
| Specificity | This antibody detects endogenous levels of WDR19/IFT144 at Human, Mouse |
| Gene Name | WDR19 KIAA1638 |
| Protein Name | WD repeat-containing protein 19 |
| Other Name | |
| Species | Human |
| Gene ID | 57728 |
| Uniprot | Q8NEZ3, |
| Species.1 | Mouse |
| Gene ID.1 | 213081 |
| Uniprot.1 | Q3UGF1 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Cell projection, cilium, photoreceptor outer segment . Localizes to photoreceptor connecting cilia, to the base of motile cilia in brain ependymal cells and to the base of and along primary cilia in kidney cells. . |
| Tissue Expression | Some isoforms are tissue-specific. Highly expressed in the prostate. Lower expression in the cerebellum, pituitary gland, fetal lung, and pancreas. In normal prostate, expressed in both basal and luminal epithelial cells. No expression detected in fibromuscular stromal cells, endothelial cells, or infiltrating lymphocytes. Uniformed expression in prostate adenocarcinoma cells. |
| Signaling_pathway | |
| Research Areas | |
| Function | As component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in cilia function and/or assembly . Essential for functional IFT-A assembly and ciliary entry of GPCRs . Associates with the BBSome complex to mediate ciliary transport (By similarity). |
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