XE7 Polyclonal Antibody
Ucallm_WP15024-50
Price range: $268.00 through $328.00
Product details
Background:
A-kinase anchoring protein 17A(AKAP17A) Homo sapiens This locus encodes a protein kinase A anchoring protein. The encoded protein is part of the spliceosome complex and is involved in the regulation of alternate splicing in some mRNA precursors. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Sep 2010],
Specifications
| Size | 50μL/100μL |
| Target | XE7 |
| Reactivity | Human |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 80kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from XE7 . at AA range: 590-670 |
| Specificity | XE7 Polyclonal Antibody detects endogenous levels of XE7 protein. |
| Gene Name | AKAP17A |
| Protein Name | A-kinase anchor protein 17A |
| Other Name | AKAP17A; / CXYorf3; / DXYS155E; / SFRS17A; / XE7; / A-kinase anchor protein 17A; / AKAP-17A; / 721P; / B-lymphocyte antigen; / Protein XE7; / Protein kinase A-anchoring protein 17A; / PRKA17A; / Splicing factor; / arginine/serine-rich 17A |
| Species | Human |
| Gene ID | 8227 |
| Uniprot | Q02040 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus speckle . |
| Tissue Expression | Widely expressed. Found in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Expressed in activated B-cells and placenta. Expressed in all cell lines tested including Jurkat-TAg, U-937 and HEK293 cells. |
| Signaling_pathway | |
| Research Areas | |
| Function | Caution:Was originally (PubMed:1438229) thought to be a cell surface protein involved in B-cell activation.,Function:Splice factor regulating alternative splice site selection for certain mRNA precursors.,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Monomer. Component of the spliceosome. Interacts with ZRANB2 and SFRS1/ASF through its Arg/Ser-rich domain.,tissue specificity:Widely expressed. Found in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Expressed in activated B-cells and placenta., |
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