Product details
Background:
XPNPEP3 rabbit pAb
Ucallm_WP8929-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | XPNPEP3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 56kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human XPNPEP3 |
| Specificity | This antibody detects endogenous levels of XPNPEP3 at Human, Mouse,Rat |
| Gene Name | XPNPEP3 |
| Protein Name | Probable Xaa-Pro aminopeptidase 3 (X-Pro aminopeptidase 3) (Aminopeptidase P3) (APP3) |
| Other Name | |
| Species | Human |
| Gene ID | 63929 |
| Uniprot | Q9NQH7, |
| Species.1 | Mouse |
| Gene ID.1 | 321003 |
| Uniprot.1 | B7ZMP1, |
| Species.2 | Rat |
| Gene ID.2 | 685823 |
| Uniprot.2 | B5DEQ3 |
| Cellular Localization | [Isoform 1]: Mitochondrion . Cytoplasm . Mainly mitochondrial. Translocates to the cytoplasm following TNFRSF1B activation. .; [Isoform 2]: Cytoplasm . |
| Tissue Expression | Isoform 1 and isoform 2 are widely expressed, with isoform 1 being more abundant. |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Leu-Pro-Ala . Also shows low activity towards peptides with Ala or Ser at the P1 position .; [Isoform 1]: Promotes TNFRSF1B-mediated phosphorylation of MAPK8/JNK1 and MAPK9/JNK2, suggesting a function as an adapter protein for TNFRSF1B; the effect is independent of XPNPEP3 peptidase activity. May inhibit apoptotic cell death induced via TNF-TNFRSF1B signaling. |
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