Product details
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ZBTB1 rabbit pAb
Ucallm_WP7241-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ZBTB1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 78kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ZBTB1 |
| Specificity | This antibody detects endogenous levels of ZBTB1 at Human, Mouse |
| Gene Name | ZBTB1 KIAA0997 |
| Protein Name | Zinc finger and BTB domain-containing protein 1 |
| Other Name | |
| Species | Human |
| Gene ID | 22890 |
| Uniprot | Q9Y2K1, |
| Species.1 | Mouse |
| Gene ID.1 | 268564 |
| Uniprot.1 | Q91VL9 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Nucleus, nucleoplasm . Localized in dot-like structures in the nucleus (PubMed:21706167). Colocalized with SMRT in nuclear bodies (PubMed:20797634). The sumoylated form is preferentially located in the nucleoplasm outside the nuclear bodies(PubMed:20797634). . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Acts as a transcriptional repressor . Represses cAMP-responsive element (CRE)-mediated transcriptional activation . In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis . Plays a key role in the transcriptional regulation of T lymphocyte development (By similarity). |
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