SKU: WP16728 Categories: ,

ZEP2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP16728-100
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Product details

Background:

This gene encodes a member of a family of closely related, large, zinc finger-containing transcription factors. The encoded protein regulates transcription by binding to regulatory regions of various cellular and viral genes that maybe involved in growth, development and metastasis. The protein contains the ZAS domain comprised of two widely separated regions of zinc finger motifs, a stretch of highly acidic amino acids and a serine/threonine-rich sequence. [provided by RefSeq, Nov 2012],

Specifications

Size50μL/100μL
TargetHIVEP2
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)269kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human ZEP2 AA range: 1975-2025
SpecificityThis antibody detects endogenous levels of ZEP2 at Human/Mouse/Rat
Gene NameHIVEP2
Protein NameTranscription factor HIVEP2
Other NameZEP2; / Transcription factor HIVEP2; / Human immunodeficiency virus type I enhancer-binding protein 2; / HIV-EP2; / MHC-binding protein 2; / MBP-2
SpeciesHuman
Gene ID3097
UniprotP31629,
Species.1Mouse
Gene ID.115273
Uniprot.1Q3UHF7,
Species.2Rat
Gene ID.229721
Uniprot.2Q00900
Cellular LocalizationNucleus.
Tissue ExpressionExpressed in brain and skeletal muscle.
Signaling_pathway
Research Areas
FunctionFunction:This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, somatostatin receptor II, and interferon-beta genes. It may act in T-cell activation.,induction:By mitogens and phorbol ester.,similarity:Contains 4 C2H2-type zinc fingers.,subunit:Interacts with TCF4.,tissue specificity:Expressed in brain and skeletal muscle.,
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