Price range: $268.00 through $328.00
Background:
disease:A chromosomal aberration involving ZFYVE19 is associated with acute myeloblastic leukemia (AML). Translocation t(11;15)(q23;q14) with MLL/HRX., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 FYVE-type zinc finger., tissue specificity:Detected in brain, heart, skeletal muscle, kidney and liver.,
| Target | ZFYVE19 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 50kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ZFYVE19. AA range:311-360 |
| Sequence | |
| Specificity | ZFYVE19 Polyclonal Antibody detects endogenous levels of ZFYVE19 protein. |
| Gene Name | ZFYVE19 |
| Protein Name | Zinc finger FYVE domain-containing protein 19 |
| Other Name | ZFYVE19; / MPFYVE; / Zinc finger FYVE domain-containing protein 19; / MLL partner containing FYVE domain |
| Species | Human |
| Gene ID-1 | 84936 |
| Uniprot | Q96K21, |
| Species.1 | Mouse |
| Gene ID-2 | |
| Uniprot.1 | Q9DAZ9 |
| Species.2 | |
| Gene ID-3 | |
| Uniprot.2 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | disease:A chromosomal aberration involving ZFYVE19 is associated with acute myeloblastic leukemia (AML). Translocation t(11; 15)(q23; q14) with MLL/HRX.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FYVE-type zinc finger.,tissue specificity:Detected in brain, heart, skeletal muscle, kidney and liver., |
| Cellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cleavage furrow . Midbody, Midbody ring . Localizes mainly on centrosomes in interphase and early mitosis. Localizes at the cleavage furrow and midbody ring in late mitosis and cytokinesis. . |
| Tissue Expression | Detected in brain, heart, skeletal muscle, kidney and liver. |
| Signaling_pathway | |
| Research Areas | |
| Function | Disease:A chromosomal aberration involving ZFYVE19 is associated with acute myeloblastic leukemia (AML). Translocation t(11; 15)(q23; q14) with MLL/HRX.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FYVE-type zinc finger.,tissue specificity:Detected in brain, heart, skeletal muscle, kidney and liver., |
| RRID |
