SKU: WP8067 Categories: ,

ZGLP1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8067-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetZGLP1
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)30kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human ZGLP1
SpecificityThis antibody detects endogenous levels of ZGLP1 at Human, Mouse
Gene NameZGLP1 GLP1
Protein NameGATA-type zinc finger protein 1 (GATA-like protein 1) (GLP-1)
Other Name
SpeciesHuman
Gene ID100125288
UniprotP0C6A0,
Species.1Mouse
Gene ID.1100009600
Uniprot.1Q1WG82
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus .
Tissue Expression
Signaling_pathway
Research Areas
FunctionTranscriptional regulator that plays a key role in germ cell development. Determines the oogenic fate by activating key genes for the oogenic program and meiotic prophase entry. Acts downstream of bone morphogenetic protein (BMP) by regulating expression of genes required for the oogenic programs, which are repressed by Polycomb activities in sexually uncommitted germ cells. Regulates expression of STRA8, a central downstream effector for the meiotic program. Acts independently of retinoic acid (RA). In males, not required for germ-cell sex determination, but required to allow the spermatogonia to efficiently accomplish the meiotic prophase.
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